ABSTRACT
Introduction@#According to the World Health Organization, 251 vaccines against coronavirus infection are under development. Although vaccination has been introduced nationwide to prevent coronavirus infection, vaccine activity varies (50-95%), and the risk of infection and complications may vary depending on the individual’s physical condition and immune activity. In addition, due to the prevalence of variant of concern, which reduces the activity of some vaccines and increases the risk of complications and mortality of COVID-19, each country and region needs to improve the knowledge and attitudes of citizens about the vaccine. there is a need to study.@*Goal@#To study the knowledge and attitudes of people who have been vaccinated against COVID-19 among the target population of Uvs province.@*Materials and methods@#The study was conducted using a descriptive method of observational research. Quantitative and qualitative methods were used to collect the survey data, and the data were collected in April 2021 through a questionnaire. A random sample of 4,212 people from 11 organizations involved in the Covid-19 vaccine was randomly selected from 24 organizations, and a total of 264 people were surveyed using 12 types of Covid-19 vaccine and analyzed using SPSS software.@*Result@#According to the results of the survey, 4212 people from 11 organizations and 24 people from each organization were randomly selected from a total of 264 people. Mostly female participants (57.5%) have been included in this study. 67.4% of the respondents reported that they do not feel fear associated with vaccination and it means that most of the participants did not show any signs of panic. 91.2% participants did not have any symptoms after the vaccination. 30.4% from total participants was used anti-inflammatory or pain relief pills after vaccination at home. 45.8% of the respondents self reported that they have moderate knowledge about Covid-19 vaccine.@*Conclusion@#Overall knowledge of people from Uvs province was insufficient. However, attitude was good enough.
ABSTRACT
Introduction@#Ciprofloxacin is a broad-spectrum antibiotic that acts against a number of bacterial infections. The study was carried out to examine the in vitro quality control tests for five leading brands of ciprofloxacin hydrochloride 500 mg tablet formulation, registered in Mongolia. The quality control parameters of five different brands of ciprofloxacin hydrochloride 500 mg tablets were determined weight variation, friability, hardness, and disintegration, dissolution and assay tests. In addition, 0 and first order kinetic models were applied for each sample.@*Method@#All the tablets were evaluated for conformity with British Pharmacopoeia (BP) and Mongolian Pharmacopoeia-National Formulary (MP-NF) standards.@*Results@#Among five brands of tablets Brand C had lower mean weight variation of 0.8% and Brand A had highest mean weight variation of 3.42%. For friability test Brand B had the lowest mean friability (0.57) and Brand A had highest mean friability (1.51). The percentages of the drug content of five brands of ciprofloxacin tablet were obtained in the following sequence: Brand E (98.4 %) < Brand C (100.3%) < Brand D (115.1%) < Brand A (138.5%) < Brand B (183.8%). E and C brands met the BP and MP-NF specifications for assay@*Conclusion@#The present study revealed that Brand A, B and D the leading brands of this tablet not met the quality control parameters as per pharmacopoeia specifications expect dissolution test for some brands (Brand A, Brand B).